Acetylenic Analogues of Chichibabin Hydrocarbon
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چکیده
منابع مشابه
Enzyme-induced inactivation of transminases by acetylenic and vinyl analogues of 4-aminobutyrate.
The reactions of two analogues of 4-aminobutyrate, namely 4-aminohex-5-ynoate and 4-aminohex-5-enoate, with three transaminases were studied. Three pure enzymes were used, aminobutyrate transaminase (EC 2.6.1.19), ornithine transaminase (EC 2.6.1.13) and aspartate transaminase (EC 2.6.1.1), and the course of the reactions was studied by observing changes in the absorption spectrum of the bound ...
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1. The affinities of the (R)- and (S)-enantiomers of hexahydro-difenidol (1) and its acetylenic analogues hexbutinol (2), hexbutinol methiodide (3) and p-fluoro-hexbutinol (4) (stereochemical purity greater than 99.8%) for muscarinic receptors in rabbit vas deferens (M1), guinea-pig atria (M2) and guinea-pig ileum (M3) were measured by dose-ratio experiments. 2. The (R)-enantiomers consistently...
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Three acetylenic brominated derivatives were isolated from a Red Sea sponge, Haliclona sp. One of them, 18-bromooctadeca-9(E),17(E)-dien-7,15-diynoic acid (3), is a known metabolite, and the other two are new compounds, (1E,5E,12E,19E)-1,22-dibromodocosa-1,5,12,19-tetraen-3,14,21-triyne (1) and methyl 18-bromooctadeca-9(E),17(E)-dien-7,15-diynoate (2) which was isolated for the first time as a ...
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Biosynthesis of prostaglandins could be stopped by several acetylenic acids. They interfered with the oxygenase activity of the sheep vesicular gland enzymic system in two distinct patterns: an instantaneous, concentration-dependent effect and a time-dependent, destructive effect. Constants for both effects are reported. No measurable oxygen consumption tias observed with the acetylenic analogs...
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ژورنال
عنوان ژورنال: Bulletin of the Chemical Society of Japan
سال: 1963
ISSN: 0009-2673,1348-0634
DOI: 10.1246/bcsj.36.799